• The estimated annual burden of injury

  2019-04-25

  

  The estimated annual burden of injury in rural Bangladesh revealed by this study was striking; 44 050 deaths and 21 million people suffering major injury events annually that were severe enough for them either to be unable to go to work or school for a day, or severe enough for them to seek treatmen

• If a structurally normal patient with polymorphic VT

  2019-04-25

  

  If a structurally normal patient with polymorphic VT/VF storm has a completely normal baseline ECG, the possible diagnosis includes CPVT and idiopathic VF. CPVT is an inherited disorder of intracellular Ca2+ handling, which can cause polymorphic VT/VF storms [10]. Abnormal SR Ca2+ release from defec

• Nakai et al showed that RTc and Tpeak end

  2019-04-25

  

  Nakai et al. showed that RTc and Tpeak-end dispersion can be used to evaluate the spatial distribution of myocardial repolarization [15,16]. We measured RTc and Tpeak-end dispersion in the acute and chronic periods in the case reported herein. Both variables were increased during the acute period af

• Development of an atrial esophageal fistula is one of

  2019-04-25

  

  Development of an atrial–esophageal fistula is one of the most dreaded complications of AF ablation [78]. A relatively large-scale nonrandomized study revealed that the anatomical risk factor of a small LA-to-esophageal distance was the most important factor in esophageal ulceration when using an ir

• The tumor microenvironment is enriched with EMVs that are

  2019-04-25

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• Any abnormality causing a loss

  2019-04-25

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• Si se rescata de estas afirmaciones

  2019-04-25

  

  Si se rescata de estas afirmaciones, en primer término, la pretensión crítica realista como fundamento de su propuesta literaria, algunos de los cambios en su entorno cultural cobran relevancia para contextualizar su interés por la ironización de la realidad dentro de la heterogeneidad de su obra. C

• The patient had an implanted Medtronic SECURA

  2019-04-24

  

  The patient had an implanted Medtronic SECURA DR device (atrial lead: Medtronic 6940/52cm, ventricular lead: Medtronic 6945/65cm). The MRI machine used was a GE Signa HDx 1.5-Tesla system. Before performing MRI, we referred to the European position statement on MRI in patients with CIEDs [3]. Becaus

• The medical environment in Asian Pacific countries is widely

  2019-04-24

  

  The medical environment in Asian-Pacific countries is widely different from that in Western countries in terms of disease prevalence, CIED implant rates, and other parameters. Moreover, there are remarkable differences in the manner patients are followed-up among the countries in the Asian-Pacific r

• br Materials and methods br Results br Discussion Although

  2019-04-24

  

  Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between E

• The authors of the NCCN non

  2019-04-24

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• br OPG RANK and RANKL

  2019-04-24

  

  OPG, RANK and RANKL contribute to the vicious cycle established between tumour jak inhibitor and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several

• Cardiogenol C In this section we will try

  2019-04-24

  

  In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma

• Landiolol is an ultra short acting superselective

  2019-04-24

  

  Landiolol is an ultra-short-acting, β1-superselective, titration intravenous β-adrenergic blocker that is rapidly metabolized to inactive forms, and has relatively smaller negative inotropic effects on the cardiac output [11]. Landiolol is more effective for controlling rapid ace inhibitor rate than

• br Conflicts of interest br Acknowledgment This work was

  2019-04-24

  

  Conflicts of interest Acknowledgment This work was supported, in part, by a grant from the Experimental Research Center ELPEN (Y97/2-12-2013). The funding source had no involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and in

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