• Programmed death ligand PD L expression is a characteristic

  2019-05-10

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• For example glutamate is increasingly recognized as

  2019-05-10

  

  For example, glutamate is increasingly recognized as one of the important dysregulated signaling molecules in cancer biology, especially in the context of bone metastasis. Commonly recognized as an excitatory neurotransmitter necessary for normal pdk 1 function, glutamate is also intimately involve

• Cierto es que Aub armar otras novelas de artista

  2019-05-10

  

  Cierto es que Aub armará otras novelas de artista semejantes congo red Jusep Torres Campalans en cuanto a modularidad y ambigüedad. Si Vida y obra de Luis Álvarez Petreña, que conoce una primera parte en 1934 y sendas ampliaciones en 1964 y 1970, se basa en la patraña del legado textual de un escrit

• El prop sito es a partir

  2019-05-10

  

  El propósito es, alkaline phosphatase inhibitors partir del “estudio de la vida, y las relaciones, los vínculos de poder”, ir descubriendo “cómo construir un movimiento que democratice hacia adentro”, sin tener como meta una presencia en las dinámicas instituidas de participación política institucio

• br LA REVISTA DEL EXILIO

  2019-05-10

  

  LA REVISTA DEL EXILIO EN TANTO PROYECTO CULTURAL Si bien existen estudios sobre la figura del exiliado —Agamben, Zuleta—, que consideran las variables históricas —Clara Lida y Pablo Yankelevich— y los esfuerzos de proporcionar corpus testimoniales con nuevas aproximaciones acerca del exilio, que

• Premature deaths of women have profound effects on families

  2019-05-10

  

  Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea

• HBV DNA levels are associated with clinically significant pa

  2019-05-10

  

  HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo

• br Discussion Bone marrow fibrosis is

  2019-05-10

  

  Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o

• The OptiVol Fluid Index OVFI which

  2019-05-09

  

  The OptiVol Fluid Index (OVFI), which is derived from changes in intrathoracic impedance, can effectively assess HF by analyzing the changes in the intrathoracic impedance detected by the original OptiVol algorithm. Small et al. previously determined that a frequent and extended threshold crossing C

• Others have observed the marked differences in clinicopathol

  2019-05-09

  

  Others have observed the marked differences in clinicopathological characteristics between breast cancer subtypes by IHC study. However, they reported that triple negative and HER2 patients are at high risk of recurrences after adjusting for age, stage and histological grade. Our data support this o

• Primarily the management of GCTs

  2019-05-09

  

  Primarily, the management of GCTs has been curettage followed by filling with bone cement [7,19]. However this has been associated with high recurrence rates. Additional treatment with adjuvants is often employed to reduce this recurrence. These adjuvants may include zinc chloride, bisphosphonates,

• azidothymidine A systematic review of population based studi

  2019-05-09

  

  A systematic review of 56 population-based studies of the incidence and early case fatality of stroke, published from 1970 to 2008, showed that, in ten low-income and middle-income countries, the age-adjusted incidence of stroke more than doubled, from 52 per 100 000 person-years in 1970–79 to 117 p

• Paraguay es puntual en la redacci n del Art culo

  2019-05-09

  

  Paraguay es puntual en la redacción del Artículo 8 de su Constitución Nacional cuando dice que “Las actividades susceptibles de producir alteración ambiental serán reguladas por la ley. Asimismo, ésta podrá restringir o prohibir aquéllas que califique peligrosas”. Describe allí las actividades que p

• Perhaps the greatest challenge however

  2019-05-09

  

  Perhaps the greatest challenge however, relates to the epidemiology of this disease and understanding the interactions that occur between the reservoir hosts (ie, monkeys), vectors, and human activities that enable transmission. Understanding these complex behavioral and ecological interactions will

• br Conclusion br Conflict of interest br Introduction Radiof

  2019-05-09

  

  Conclusion Conflict of interest Introduction Radiofrequency catheter ablation has been established as an effective and curative therapy for Wolff-Parkinson-White Syndrome [1–4]. Therefore, prediction of the precise location of an accessory pathway (AP) prior to the ablation procedure is of

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